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crb2a


Official Full Name
crumbs cell polarity complex component 2a
Organism
Danio rerio
Gene ID
723994
Background
Predicted to enable calcium ion binding activity. Involved in retina morphogenesis in camera-type eye. Acts upstream of or within several processes, including apical protein localization; embryonic retina morphogenesis in camera-type eye; and heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules. Located in plasma membrane. Part of protein-containing complex. Is expressed in epidermal cell; integument; nervous system; otic vesicle; and presumptive neural retina. Human ortholog(s) of this gene implicated in focal segmental glomerulosclerosis 9 and ventriculomegaly - cystic kidney disease. Orthologous to human CRB2 (crumbs cell polarity complex component 2). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
crb2

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