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col2a1a


Official Full Name
collagen, type II, alpha 1a
Organism
Danio rerio
Gene ID
562496
Background
Predicted to be an extracellular matrix structural constituent conferring tensile strength. Acts upstream of or within several processes, including embryonic skeletal system development; neural crest cell migration; and notochord development. Predicted to be located in extracellular region. Predicted to be part of collagen trimer. Predicted to be active in collagen-containing extracellular matrix and extracellular space. Is expressed in several structures, including endoderm; fin; floor plate; head; and skeletal system. Human ortholog(s) of this gene implicated in Stickler syndrome (multiple); bone disease (multiple); cleft palate; eye disease (multiple); and multiple epiphyseal dysplasia with myopia and deafness. Orthologous to human COL2A1 (collagen type II alpha 1 chain). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
col2a1; coll2a1; fb38c06; fc10c01; wu:fb38c06; wu:fc10c01

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