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cdkn1bb


Official Full Name
cyclin dependent kinase inhibitor 1Bb
Organism
Danio rerio
Gene ID
368329
Background
Predicted to enable cyclin-dependent protein serine/threonine kinase inhibitor activity and protein-folding chaperone binding activity. Predicted to be involved in G1/S transition of mitotic cell cycle; negative regulation of epithelial cell proliferation; and negative regulation of mitotic cell cycle. Predicted to act upstream of or within regulation of cell cycle. Predicted to be located in endosome. Predicted to be active in cytoplasm and nucleus. Is expressed in several structures, including axis; nervous system; pectoral fin; polster; and solid lens vesicle. Human ortholog(s) of this gene implicated in acute myeloid leukemia; breast cancer; multiple endocrine neoplasia type 4; and myelodysplastic syndrome. Orthologous to human CDKN1B (cyclin dependent kinase inhibitor 1B). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
cdkn1b; fb64g10; sb:cb611; im:7152670; wu:fb63g10; wu:fb64g10; wu:fe18e03

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