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cdk5r1b


Official Full Name
cyclin dependent kinase 5, regulatory subunit 1b (p35)
Organism
Danio rerio
Gene ID
436788
Background
Predicted to enable cyclin-dependent protein serine/threonine kinase activator activity and protein kinase binding activity. Acts upstream of or within amacrine cell differentiation; embryonic retina morphogenesis in camera-type eye; and retina layer formation. Predicted to be located in several cellular components, including nucleus; perikaryon; and perinuclear region of cytoplasm. Predicted to be part of protein kinase 5 complex. Predicted to be active in cytoplasm and growth cone. Is expressed in basal plate midbrain region and nervous system. Human ortholog(s) of this gene implicated in Alzheimer's disease. Orthologous to human CDK5R1 (cyclin dependent kinase 5 regulatory subunit 1). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
p35; cdk5r1; zgc:92814

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