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c3a.1


Official Full Name
complement C3a, tandem duplicate 1
Organism
Danio rerio
Gene ID
321046
Background
Predicted to enable endopeptidase inhibitor activity and serine-type endopeptidase activity. Acts upstream of or within chordate embryonic development and positive regulation of neutrophil migration. Predicted to be located in extracellular space. Is expressed in several structures, including gill; heart; liver; pleuroperitoneal region; and yolk syncytial layer. Human ortholog(s) of this gene implicated in several diseases, including complement deficiency (multiple); macular degeneration (multiple); paroxysmal nocturnal hemoglobinuria; sickle cell anemia; and silicosis. Orthologous to human C3 (complement C3). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
C3; c3a; C3-1; cb26; sb:cb26; wu:fi34b03; wu:fj86e11; si:dkey-76b14.4

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