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C18ORF56


Official Full Name
MyoD family inhibitor
Organism
Homo sapiens
Gene ID
4188
Background
This protein is a transcription factor that negatively regulates other myogenic family proteins. Studies of the mouse homolog, I-mf, show that it interferes with myogenic factor function by masking nuclear localization signals and preventing DNA binding. Knockout mouse studies show defects in the formation of vertebrae and ribs that also involve cartilage formation in these structures. [provided by RefSeq, Jul 2008]
Synonyms
MDFI; I-MF; I-mfa

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