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bmpr1aa


Official Full Name
bone morphogenetic protein receptor, type IAa
Organism
Danio rerio
Gene ID
58145
Background
Predicted to enable transforming growth factor beta receptor activity, type I. Acts upstream of or within with a positive effect on SMAD protein signal transduction. Acts upstream of or within BMP signaling pathway; circulatory system development; and dorsal/ventral pattern formation. Part of BMP receptor complex. Is expressed in several structures, including blastoderm; digestive system; germ ring; ovarian follicle; and posterior cardinal vein. Human ortholog(s) of this gene implicated in hereditary mixed polyposis syndrome 2; intestinal disease; and juvenile polyposis syndrome. Orthologous to human BMPR1A (bone morphogenetic protein receptor type 1A). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
BR1a; alk3; alk3tr; bmpr1a; BMPR-IA; zgc:136731

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