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AU040829


Official Full Name
Rho GTPase activating protein 44
Organism
Mus musculus
Gene ID
216831
Background
Enables GTPase activator activity and small GTPase binding activity. Involved in several processes, including negative regulation of Rac protein signal transduction; regulation of dendritic spine morphogenesis; and regulation of neurotransmitter receptor transport, endosome to postsynaptic membrane. Located in dendritic spine. Is active in glutamatergic synapse. Is expressed in central nervous system; olfactory epithelium; respiratory system; and retina. Human ortholog(s) of this gene implicated in acquired immunodeficiency syndrome and skin melanoma. Orthologous to human ARHGAP44 (Rho GTPase activating protein 44). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
Arhgap44; Rich2; 6330543G20

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