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arhgef7b


Official Full Name
Rho guanine nucleotide exchange factor (GEF) 7b
Organism
Danio rerio
Gene ID
494081
Background
Predicted to enable guanyl-nucleotide exchange factor activity. Acts upstream of or within several processes, including endothelial cell proliferation; epiboly involved in gastrulation with mouth forming second; and protein localization to adherens junction. Predicted to be active in cytoplasm and lamellipodium. Is expressed in several structures, including EVL; axial vasculature; hatching gland; nervous system; and periderm. Used to study cerebrovascular disease. Orthologous to human ARHGEF7 (Rho guanine nucleotide exchange factor 7). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
bbh; bpix; arhgef7; im:7142367; wu:fc35h08; zgc:101775

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