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apoa1a


Official Full Name
apolipoprotein A-Ia
Organism
Danio rerio
Gene ID
30355
Background
Predicted to enable several functions, including cholesterol transfer activity; high-density lipoprotein particle binding activity; and phosphatidylcholine-sterol O-acyltransferase activator activity. Predicted to be involved in several processes, including acylglycerol homeostasis; cholesterol efflux; and phospholipid efflux. Predicted to act upstream of or within cholesterol biosynthetic process and cholesterol transport. Located in extracellular region. Is expressed in digestive system; ovary; ventral telencephalon; and yolk syncytial layer. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); familial hypercholesterolemia; hypolipoproteinemia (multiple); metabolic dysfunction-associated steatohepatitis; and systemic lupus erythematosus. Orthologous to human APOA1 (apolipoprotein A1). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
apoa; cb49; apoa1; Apo-AIa; ApoA-Ia; wu:fb33f01; zgc:103718

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