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ANTXR1


Official Full Name
ANTXR cell adhesion molecule 1
Organism
Homo sapiens
Gene ID
84168
Background
This gene encodes a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. The encoded protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor (EF) and lethal factor (LF) disrupt normal cellular processes. Three alternatively spliced variants that encode different protein isoforms have been described. [provided by RefSeq, Oct 2008]
Synonyms
ATR; GAPO; TEM8

Cat.No. Product Name Price
SHG061669 shRNA set against Mouse Antxr1(NM_054041.2) Inquiry
SHH237454 shRNA set against Human ANTXR1 (NM_018153.3) Inquiry
SHH237458 shRNA set against Mouse ANTXR1 (NM_054041.2) Inquiry
SHH237462 shRNA set against Rat ANTXR1 (NM_001044249.2) Inquiry
Cat.No. Product Name Price
CDCS414666 Human ANTXR1 ORF Clone (BC012074) Inquiry
CDFR004774 Rat Antxr1 cDNA Clone(NM_001044249.2) Inquiry
MiUTR1M-01516 ANTXR1 miRNA 3'UTR clone Inquiry
MiUTR3H-08427 ANTXR1 miRNA 3'UTR clone Inquiry
MiUTR3H-08428 ANTXR1 miRNA 3'UTR clone Inquiry
MiUTR4H-TG00376 ANTXR1 miRNA 3'UTR clone Inquiry
CDCB159805 Human ANTXR1 ORF clone (BC012074) Inquiry
CDCB183322 Rabbit ANTXR1 ORF clone (XM_002709824.2) Inquiry
CDCR264653 Mouse Antxr1 ORF Clone(NM_054041.2) Inquiry
CDCR371807 Rat Antxr1 ORF Clone(NM_001044249.2) Inquiry
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