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ABCC2


Official Full Name
ATP binding cassette subfamily C member 2
Organism
Homo sapiens
Gene ID
1244
Background
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein is expressed in the canalicular (apical) part of the hepatocyte and functions in biliary transport. Substrates include anticancer drugs such as vinblastine; therefore, this protein appears to contribute to drug resistance in mammalian cells. Several different mutations in this gene have been observed in patients with Dubin-Johnson syndrome (DJS), an autosomal recessive disorder characterized by conjugated hyperbilirubinemia. [provided by RefSeq, Jul 2008]
Synonyms
atpa2; cb702; atp1a2; atp[a]2; fa10d04; fa10d05; wu:fa10d05

Cat.No. Product Name Price
AD00456Z Human Abcc2 adenoviral particles Inquiry
Cat.No. Product Name Price
SHG023969 shRNA set against Human ABCC2(NM_000392.3) Inquiry
SHG024055 shRNA set against Rat Abcc2(NM_012833.1) Inquiry
SHG024101 shRNA set against Mouse Abcc2(NM_013806.2) Inquiry
SHH229114 shRNA set against Human Abcc2 (NM_000392.3) Inquiry
SHH229118 shRNA set against Mouse Abcc2 (NM_013806.2) Inquiry
SHH229122 shRNA set against Rat Abcc2 (NM_012833.1) Inquiry
SHW016753 shRNA set against Danio rerio ABCC2 (NM_200589) Inquiry
Cat.No. Product Name Price
CDFL000754 Mouse Abcc2 cDNA Clone(NM_013806.2) Inquiry
CDFR010689 Rat Abcc2 cDNA Clone(NM_012833.1) Inquiry
MiUTR1H-00040 ABCC2 miRNA 3'UTR clone Inquiry
MiUTR1M-01040 ABCC2 miRNA 3'UTR clone Inquiry
MiUTR1R-00028 ABCC2 miRNA 3'UTR clone Inquiry
CDCB178228 Danio rerio ABCC2 ORF Clone (NM_200589) Inquiry
CDCB191766 Rabbit ABCC2 ORF clone (XM_008270326.1) Inquiry
CDCH014575 Human Abcc2 ORF clone(NM_000392.3) Inquiry
CDCR022930 Mouse Abcc2 ORF clone (NM_013806.2) Inquiry
CDCR377692 Rat Abcc2 ORF Clone(NM_012833.1) Inquiry
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