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ZMPSTE24


Official Full Name
zinc metallopeptidase STE24
Organism
Homo sapiens
Gene ID
10269
Background
This gene encodes a member of the peptidase M48A family. The encoded protein is a zinc metalloproteinase involved in the two step post-translational proteolytic cleavage of carboxy terminal residues of farnesylated prelamin A to form mature lamin A. Mutations in this gene have been associated with mandibuloacral dysplasia and restrictive dermopathy. [provided by RefSeq, Jul 2008]
Synonyms
HGPS; PRO1; FACE1; RSDM1; STE24; FACE-1; Ste24p

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