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ZNF420

Official Full Name
zinc finger protein 420
Organism
Homo sapiens
GeneID
147923
Background
The protein encoded by this gene is a KRAB-type zinc finger protein that negatively-regulates p53-mediated apoptosis. Under stress conditions, the encoded protein is phosphorylated by ATM and dissociates from p53, which activates p53 and initiates apoptosis. [provided by RefSeq, Jul 2016]
Synonyms
APAK;

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