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ZEB2

Official Full Name
zinc finger E-box binding homeobox 2
Organism
Homo sapiens
GeneID
9839
Background
The protein encoded by this gene is a member of the Zfh1 family of 2-handed zinc finger/homeodomain proteins. It is located in the nucleus and functions as a DNA-binding transcriptional repressor that interacts with activated SMADs. Mutations in this gene are associated with Hirschsprung disease/Mowat-Wilson syndrome. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Jan 2010]
Synonyms
SIP1; SIP-1; ZFHX1B; HSPC082; SMADIP1;

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