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zeb1b


Official Full Name
zinc finger E-box binding homeobox 1b
Organism
Danio rerio
Gene ID
114425
Background
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within several processes, including gastrulation; regulation of cell-cell adhesion involved in gastrulation; and regulation of gastrulation. Predicted to be located in nucleus. Is expressed in several structures, including cranial ganglion; hypoblast; intestine; neural plate; and segmental plate. Human ortholog(s) of this gene implicated in Fuchs' endothelial dystrophy and posterior polymorphous corneal dystrophy 3. Orthologous to human ZEB1 (zinc finger E-box binding homeobox 1). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
zeb1; zfhx1; kheper; ZFH/[d]EF1

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