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ZBTB33


Official Full Name
zinc finger and BTB domain containing 33
Organism
Homo sapiens
Gene ID
10009
Background
This gene encodes a transcriptional regulator with bimodal DNA-binding specificity, which binds to methylated CGCG and also to the non-methylated consensus KAISO-binding site TCCTGCNA. The protein contains an N-terminal POZ/BTB domain and 3 C-terminal zinc finger motifs. It recruits the N-CoR repressor complex to promote histone deacetylation and the formation of repressive chromatin structures in target gene promoters. It may contribute to the repression of target genes of the Wnt signaling pathway, and may also activate transcription of a subset of target genes by the recruitment of catenin delta-2 (CTNND2). Its interaction with catenin delta-1 (CTNND1) inhibits binding to both methylated and non-methylated DNA. It also interacts directly with the nuclear import receptor Importin-2 (also known as karyopherin alpha2 or RAG cohort 1), which may mediate nuclear import of this protein. Alternatively spliced transcript variants encoding the same protein have been identified.[provided by RefSeq, May 2010]
Synonyms
ZNF348; ZNF-kaiso

Cat.No. Product Name Price
SHH449064 shRNA set against Human ZBTB33 (NM_006777.3) Inquiry
SHH449068 shRNA set against Mouse ZBTB33 (NM_020256.2) Inquiry
SHH449072 shRNA set against Rat ZBTB33 (NM_001109314.1) Inquiry
SHL142050 shRNA set against Human ZBTB33(NM_006777.3) Inquiry
SHL142068 shRNA set against Mouse Zbtb33(NM_001079513.1) Inquiry
SHL142086 shRNA set against Mouse Zbtb33(NM_020256.2) Inquiry
SHW002504 shRNA set against Chicken ZBTB33 (NM_001079729) Inquiry
SHW011701 shRNA set against Danio rerio ZBTB33 (NM_001100008) Inquiry
Cat.No. Product Name Price
CDFH021481 Human ZBTB33 cDNA Clone(NM_001184742.1) Inquiry
CDFH021482 Human ZBTB33 cDNA Clone(NM_006777.3) Inquiry
CDFR008901 Rat Zbtb33 cDNA Clone(NM_001109314.1) Inquiry
MiUTR1H-11379 ZBTB33 miRNA 3'UTR clone Inquiry
MiUTR1M-12897 ZBTB33 miRNA 3'UTR clone Inquiry
MiUTR1M-12898 ZBTB33 miRNA 3'UTR clone Inquiry
SKO0150 ZBTB33 Validated sgRNA vector Inquiry
CDCB163979 Chicken ZBTB33 ORF Clone (NM_001079729) Inquiry
CDCB173176 Danio rerio ZBTB33 ORF Clone (NM_001100008) Inquiry
CDCB188482 Rabbit ZBTB33 ORF clone (XM_002720400.2) Inquiry
CDCH102382 Mouse Zbtb33 ORF clone (NM_001079513.1) Inquiry
CDCR254771 Mouse Zbtb33 ORF Clone(NM_020256.2) Inquiry
CDCR293679 Human ZBTB33 ORF Clone(NM_006777.3) Inquiry
CDCR357480 Human ZBTB33 ORF Clone(NM_001184742.1) Inquiry
CDCR375900 Rat Zbtb33 ORF Clone(NM_001109314.1) Inquiry
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