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ZAP70


Official Full Name
zeta chain of T cell receptor associated protein kinase 70
Organism
Homo sapiens
Gene ID
7535
Background
This gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T-cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation, functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene cause selective T-cell defect, a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T-cells. Two transcript variants that encode different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Synonyms
SRK; STD; TZK; STCD; IMD48; ADMIO2; ZAP-70

Cat.No. Product Name Price
AD17910Z Human ZAP70 adenoviral particles Inquiry
Cat.No. Product Name Price
SHL141096 shRNA set against Human ZAP70(NM_001079.3) Inquiry
SHH448796 shRNA set against Human ZAP70 (NM_001079.3) Inquiry
SHH448800 shRNA set against Mouse ZAP70 (NM_009539.2) Inquiry
SHH448804 shRNA set against Rat ZAP70 (NM_001012002.1) Inquiry
SHL141006 shRNA set against Rat Zap70(NM_001012002.1) Inquiry
SHL141042 shRNA set against Mouse Zap70(NM_009539.2) Inquiry
SHL141078 shRNA set against Human ZAP70(NM_207519.1) Inquiry
SHW008656 shRNA set against Danio rerio ZAP70 (NM_001020589) Inquiry
Cat.No. Product Name Price
CDCH102242 human ZAP70 ORF clone (NM_207519.1) Inquiry
CDCH102246 Mouse Zap70 ORF clone (NM_009539.2) Inquiry
CDFG013879 Human ZAP70 cDNA Clone(NM_207519.1) Inquiry
CDFH021447 Human ZAP70 cDNA Clone(NM_001079.3) Inquiry
CDFH021448 Human ZAP70 cDNA Clone(NM_001079.3) Inquiry
CDFR002433 Rat Zap70 cDNA Clone(NM_001012002.1) Inquiry
MiUTR1H-11360 ZAP70 miRNA 3'UTR clone Inquiry
MiUTR1H-11361 ZAP70 miRNA 3'UTR clone Inquiry
MiUTR1M-12887 ZAP70 miRNA 3'UTR clone Inquiry
MiUTR1R-08649 ZAP70 miRNA 3'UTR clone Inquiry
CDCB170131 Danio rerio ZAP70 ORF Clone (NM_001020589) Inquiry
CDCB192468 Rabbit ZAP70 ORF clone (XM_008253649.1) Inquiry
CDCR369349 Rat Zap70 ORF Clone(NM_001012002.1) Inquiry
CDCS407251 Human ZAP70 ORF Clone (BC039039) Inquiry
CDCS407252 Human ZAP70 ORF Clone (BC053878) Inquiry
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