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YWHAQ

Official Full Name
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta
Organism
Homo sapiens
GeneID
10971
Background
This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse and rat orthologs. This gene is upregulated in patients with amyotrophic lateral sclerosis. It contains in its 5' UTR a 6 bp tandem repeat sequence which is polymorphic, however, there is no correlation between the repeat number and the disease. [provided by RefSeq, Jul 2008]
Synonyms
1C5; HS1; 14-3-3;

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