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XRCC6BP1

Official Full Name
ATP23 metallopeptidase and ATP synthase assembly factor homolog
Organism
Homo sapiens
GeneID
91419
Background
The protein encoded by this gene is amplified in glioblastomas and interacts with the DNA binding subunit of DNA-dependent protein kinase. This kinase is involved in double-strand break repair (DSB), and higher expression of the encoded protein increases the efficiency of DSB. In addition, comparison to orthologous proteins strongly suggests that this protein is a metalloprotease important in the biosynthesis of mitochondrial ATPase. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2016]
Synonyms
ATP23; KUB3; XRCC6BP1;

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