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WNT4


Official Full Name
Wnt family member 4
Organism
Homo sapiens
Gene ID
54361
Background
The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family, and is the first signaling molecule shown to influence the sex-determination cascade. It encodes a protein which shows 98% amino acid identity to the Wnt4 protein of mouse and rat. This gene and a nuclear receptor known to antagonize the testis-determining factor play a concerted role in both the control of female development and the prevention of testes formation. This gene and another two family members, WNT2 and WNT7B, may be associated with abnormal proliferation in breast tissue. Mutations in this gene can result in Rokitansky-Kuster-Hauser syndrome and in SERKAL syndrome. [provided by RefSeq, Jul 2008]
Synonyms
WNT-4; SERKAL

Cat.No. Product Name Price
SHH447304 shRNA set against Human WNT4 (NM_030761.4) Inquiry
SHH447308 shRNA set against Mouse WNT4 (NM_009523.2) Inquiry
SHW005290 shRNA set against Chicken WNT4 (NM_204783) Inquiry
Cat.No. Product Name Price
CDCB195377 Rabbit WNT4 ORF clone (XM_008265713.1) Inquiry
CDCS415991 Human WNT4 ORF Clone (BC057781) Inquiry
MiUTR1H-11280 WNT4 miRNA 3'UTR clone Inquiry
CDCB157169 Mouse WNT4 ORF clone (NM_009523.1) Inquiry
CDCB166765 Chicken WNT4 ORF Clone (NM_204783) Inquiry
CDCR380234 Rat Wnt4 ORF Clone(NM_053402.2) Inquiry
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