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WNT1


Official Full Name
Wnt family member 1
Organism
Homo sapiens
Gene ID
7471
Background
The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It is very conserved in evolution, and the protein encoded by this gene is known to be 98% identical to the mouse Wnt1 protein at the amino acid level. The studies in mouse indicate that the Wnt1 protein functions in the induction of the mesencephalon and cerebellum. This gene was originally considered as a candidate gene for Joubert syndrome, an autosomal recessive disorder with cerebellar hypoplasia as a leading feature. However, further studies suggested that the gene mutations might not have a significant role in Joubert syndrome. This gene is clustered with another family member, WNT10B, in the chromosome 12q13 region. [provided by RefSeq, Jul 2008]
Synonyms
INT1; OI15; BMND16

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SHH447196 shRNA set against Human WNT1 (NM_005430.3) Inquiry
SHH447200 shRNA set against Mouse WNT1 (NM_021279.4) Inquiry
SHH447204 shRNA set against Rat WNT1 (NM_001105714.1) Inquiry
SHW013809 shRNA set against Danio rerio WNT1 (NM_001201398) Inquiry
Cat.No. Product Name Price
CDFR005306 Rat Wnt1 cDNA Clone(NM_001105714.1) Inquiry
MiUTR1H-11275 WNT1 miRNA 3'UTR clone Inquiry
MiUTR1M-12807 WNT1 miRNA 3'UTR clone Inquiry
CDCB175284 Danio rerio WNT1 ORF Clone (NM_001201398) Inquiry
CDCB185519 Rabbit WNT1 ORF clone (XM_008256407.1) Inquiry
CDCR255028 Mouse Wnt1 ORF Clone(NM_021279.4) Inquiry
CDCR371896 Rat Wnt1 ORF Clone(NM_001105714.1) Inquiry
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