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WIPI2

Official Full Name
WD repeat domain, phosphoinositide interacting 2
Organism
Homo sapiens
GeneID
26100
Background
WD40 repeat proteins are key components of many essential biologic functions. They regulate the assembly of multiprotein complexes by presenting a beta-propeller platform for simultaneous and reversible protein-protein interactions. Members of the WIPI subfamily of WD40 repeat proteins, such as WIPI2, have a 7-bladed propeller structure and contain a conserved motif for interaction with phospholipids (Proikas-Cezanne et al., 2004 [PubMed 15602573]).[supplied by OMIM, Mar 2008]
Synonyms
Atg21; ATG18B; CGI-50; IDDSSA; WIPI-2;

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