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WHSC2


Official Full Name
negative elongation factor complex member A
Organism
Homo sapiens
Gene ID
7469
Background
This gene is expressed ubiquitously with higher levels in fetal than in adult tissues. It encodes a protein sharing 93% sequence identity with the mouse protein. Wolf-Hirschhorn syndrome (WHS) is a malformation syndrome associated with a hemizygous deletion of the distal short arm of chromosome 4. This gene is mapped to the 165 kb WHS critical region, and may play a role in the phenotype of the WHS or Pitt-Rogers-Danks syndrome. The encoded protein is found to be capable of reacting with HLA-A2-restricted and tumor-specific cytotoxic T lymphocytes, suggesting a target for use in specific immunotherapy for a large number of cancer patients. This protein has also been shown to be a member of the NELF (negative elongation factor) protein complex that participates in the regulation of RNA polymerase II transcription elongation. [provided by RefSeq, Jul 2008]
Synonyms
NELFA; WHSC2; NELF-A; P/OKcl.15

Cat.No. Product Name Price
SHH447000 shRNA set against Human WHSC2 (NM_005663.4) Inquiry
SHH447004 shRNA set against Mouse WHSC2 (NM_011914.2) Inquiry
SHH447008 shRNA set against Rat WHSC2 (NM_001008339.1) Inquiry
SHL135102 shRNA set against Mouse Whsc2(NM_011914.2) Inquiry
SHL135156 shRNA set against Rat Whsc2(NM_001008339.1) Inquiry
Cat.No. Product Name Price
CDFR001801 Rat Whsc2 cDNA Clone(NM_001008339.1) Inquiry
MiUTR1M-12800 WHSC2 miRNA 3'UTR clone Inquiry
MiUTR1R-08588 WHSC2 miRNA 3'UTR clone Inquiry
MiUTR3H-08153 WHSC2 miRNA 3'UTR clone Inquiry
CDCH101330 Mouse Whsc2 ORF clone (NM_011914.2) Inquiry
CDCR368868 Rat Whsc2 ORF Clone(NM_001008339.1) Inquiry
CDCS412357 Human WHSC2 ORF Clone (BC002764) Inquiry
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