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WDR85

Official Full Name
diphthamide biosynthesis 7
Organism
Homo sapiens
GeneID
92715
Background
Diphthamide is a post-translationally modified histidine residue present in elongation factor 2, and is the target of diphtheria toxin. This gene encodes a protein that contains a WD-40 domain, and is thought to be involved in diphthamide biosynthesis. A similar protein in yeast functions as a methylesterase, converting methylated diphthine to diphthine, which can then undergo amidation to produce diphthamide. [provided by RefSeq, Oct 2016]
Synonyms
DPH7; RRT2; WDR85; C9orf112;

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