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VPS72


Official Full Name
vacuolar protein sorting 72 homolog
Organism
Homo sapiens
Gene ID
6944
Background
The protein encoded by this gene is a shared subunit of two multi-component complexes, the histone acetyltransferase complex TRRAP/TIP60 as well as the chromatin remodeling SRCAP-containing complex. The TRRAP/TIP60 complex acetylates nucleosomal histones important for transcriptional regulation, double strand DNA break repair and apoptosis. The SRCAP-containing complex catalyzes the exchange of histone H2A with the histone variant Htz1 (H2AFZ) into nucleosomes. This protein may be responsible for binding H2AFZ, which has a role in chromosome segregation. This protein may also have a role in regulating long-term hematopoietic stem cell activity. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Aug 2012]
Synonyms
YL1; CFL1; Swc2; YL-1; TCFL1

Cat.No. Product Name Price
SHH445120 shRNA set against Human VPS72 (NM_005997.2) Inquiry
SHH445124 shRNA set against Mouse VPS72 (NM_009336.2) Inquiry
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SHL128620 shRNA set against Mouse Vps72(NM_009336.2) Inquiry
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CDCB195176 Rabbit VPS72 ORF clone (NM_001171300.1) Inquiry
CDCR246876 Mouse Vps72 ORF Clone(NM_009336.2) Inquiry
CDCR374416 Rat Vps72 ORF Clone(NM_001107695.1) Inquiry
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