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VPREB1

Official Full Name
V-set pre-B cell surrogate light chain 1
Organism
Homo sapiens
GeneID
7441
Background
The protein encoded by this gene belongs to the immunoglobulin superfamily and is expressed selectively at the early stages of B cell development, namely, in proB and early preB cells. This gene encodes the iota polypeptide chain that is associated with the Ig-mu chain to form a molecular complex which is expressed on the surface of pre-B cells. The complex is thought to regulate Ig gene rearrangements in the early steps of B-cell differentiation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]
Synonyms
IGI; IGVPB; VPREB; CD179a;

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