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vdra


Official Full Name
vitamin D receptor a
Organism
Danio rerio
Gene ID
30076
Background
Enables calcitriol binding activity; lithocholic acid binding activity; and nuclear receptor activity. Contributes to DNA-binding transcription factor activity and vitamin D response element binding activity. Acts upstream of or within several processes, including calcium ion homeostasis; determination of heart left/right asymmetry; and hematopoietic stem cell proliferation. Predicted to be located in cytoplasm. Predicted to be active in nucleus. Is expressed in several structures, including brain; head; heart; integument; and pleuroperitoneal region. Used to study hematopoietic system disease and vitamin D-dependent rickets. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); carcinoma (multiple); liver disease (multiple); lung disease (multiple); and melanoma (multiple). Orthologous to human VDR (vitamin D receptor). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
vdr; VDR-A; nr1i1a; NR1I1-A; VDRalpha

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