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vcla

Official Full Name
vinculin a
Organism
Danio rerio
GeneID
552980
Background
Predicted to enable alpha-catenin binding activity and beta-catenin binding activity. Involved in heart contraction. Acts upstream of or within atrioventricular valve morphogenesis; membrane repolarization during cardiac muscle cell action potential; and sarcomere organization. Located in adherens junction. Is active in focal adhesion. Is expressed in several structures, including heart; lens; pectoral fin; solid lens vesicle; and somite. Human ortholog(s) of this gene implicated in dilated cardiomyopathy; dilated cardiomyopathy 1W; hypertrophic cardiomyopathy; and hypertrophic cardiomyopathy 15. Orthologous to human VCL (vinculin). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
vcl; im:6902790; hm:zehn2160;

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