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UMOD


Official Full Name
uromodulin
Organism
Homo sapiens
Gene ID
7369
Background
The protein encoded by this gene is the most abundant protein in mammalian urine under physiological conditions. Its excretion in urine follows proteolytic cleavage of the ectodomain of its glycosyl phosphatidylinosital-anchored counterpart that is situated on the luminal cell surface of the loop of Henle. This protein may act as a constitutive inhibitor of calcium crystallization in renal fluids. Excretion of this protein in urine may provide defense against urinary tract infections caused by uropathogenic bacteria. Defects in this gene are associated with the renal disorders medullary cystic kidney disease-2 (MCKD2), glomerulocystic kidney disease with hyperuricemia and isosthenuria (GCKDHI), and familial juvenile hyperuricemic nephropathy (FJHN). Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2013]
Synonyms
THP; FJHN; HNFJ; THGP; HNFJ1; MCKD2; ADTKD1; ADMCKD2

Cat.No. Product Name Price
SHH223962 shRNA set against Human UMOD(NM_001008389.1) Inquiry
SHH440416 shRNA set against Human UMOD (NM_003361.2) Inquiry
SHH440420 shRNA set against Mouse UMOD (NM_009470.4) Inquiry
SHH440424 shRNA set against Rat UMOD (NM_017082.1) Inquiry
SHL114372 shRNA set against Rat Umod(NM_017082.1) Inquiry
Cat.No. Product Name Price
CDCB192225 Rabbit UMOD ORF clone (XM_008257768.1) Inquiry
CDCL186687 Mouse UMOD ORF clone(NM_009470.4) Inquiry
CDCS406357 Human UMOD ORF Clone (BC035975) Inquiry
CDFH020855 Human UMOD cDNA Clone(NM_001008389.1) Inquiry
CDFH020856 Human UMOD cDNA Clone(NM_003361.2) Inquiry
CDFR011149 Rat Umod cDNA Clone(NM_017082.1) Inquiry
MiUTR1H-11006 UMOD miRNA 3'UTR clone Inquiry
MiUTR1R-08348 UMOD miRNA 3'UTR clone Inquiry
MiUTR3H-02388 UMOD miRNA 3'UTR clone Inquiry
CDCR285484 Human UMOD ORF Clone(NM_003361.2) Inquiry
CDCR340399 Human UMOD ORF Clone(NM_001008389.1) Inquiry
CDCR378052 Rat Umod ORF Clone(NM_017082.1) Inquiry
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