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UGT1A10


Official Full Name
UDP glucuronosyltransferase family 1 member A10
Organism
Homo sapiens
Gene ID
54575
Background
This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. The enzyme encoded by this gene has glucuronidase activity on mycophenolic acid, coumarins, and quinolines. [provided by RefSeq, Jul 2008]
Synonyms
GNT1; UGT1; UDPGT; UGT1A; UGT1J; UGT-1A; UGT-1J; UGT1.1; UGT1A1; UGT1-01; UGT1-10; UGT1.10; hUG-BR1

Cat.No. Product Name Price
SHH440060 shRNA set against Human UGT1A10 (NM_019075.2) Inquiry
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CDCR277069 Mouse Ugt1a10 ORF Clone(NM_201641.2) Inquiry
CDCS419908 Human UGT1A10 ORF Clone (BC020971) Inquiry
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