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UCP3


Official Full Name
uncoupling protein 3
Organism
Homo sapiens
Gene ID
7352
Background
Mitochondrial uncoupling proteins (UCP) are members of the larger family of mitochondrial anion carrier proteins (MACP). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. The different UCPs have tissue-specific expression; this gene is primarily expressed in skeletal muscle. This gene's protein product is postulated to protect mitochondria against lipid-induced oxidative stress. Expression levels of this gene increase when fatty acid supplies to mitochondria exceed their oxidation capacity and the protein enables the export of fatty acids from mitochondria. UCPs contain the three solcar protein domains typically found in MACPs. Two splice variants have been found for this gene.[provided by RefSeq, Nov 2008]
Synonyms
SLC25A9

Cat.No. Product Name Price
SHH439896 shRNA set against Human UCP3 (NM_003356.3) Inquiry
SHH439900 shRNA set against Mouse UCP3 (NM_009464.3) Inquiry
SHH439904 shRNA set against Rat UCP3 (NM_013167.2) Inquiry
SHL104940 shRNA set against Rat Ucp3(NM_013167.2) Inquiry
SHL105004 shRNA set against Mouse Ucp3(NM_009464.3) Inquiry
SHW004626 shRNA set against Chicken UCP3 (NM_204107) Inquiry
SHW016562 shRNA set against Danio rerio UCP3 (NM_200353) Inquiry
Cat.No. Product Name Price
CDCR247247 Mouse Ucp3 ORF Clone(NM_009464.3) Inquiry
CDFR010964 Rat Ucp3 cDNA Clone(NM_013167.2) Inquiry
MiUTR1R-08330 UCP3 miRNA 3'UTR clone Inquiry
MiUTR3H-04621 UCP3 miRNA 3'UTR clone Inquiry
MiUTR3H-04622 UCP3 miRNA 3'UTR clone Inquiry
CDCB166101 Chicken UCP3 ORF Clone (NM_204107) Inquiry
CDCB178037 Danio rerio UCP3 ORF Clone (NM_200353) Inquiry
CDCB182544 Rabbit UCP3 ORF clone (XM_008264096.1) Inquiry
CDCR378001 Rat Ucp3 ORF Clone(NM_013167.2) Inquiry
CDCS411270 Human UCP3 ORF Clone (BC008392) Inquiry
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