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USP20


Official Full Name
ubiquitin specific peptidase 20
Organism
Homo sapiens
Gene ID
10868
Background
This gene encodes a ubiquitin specific processing protease that was first identified as a substrate of the VHL (von Hippel-Lindau disease) protein E3 ubiquitin ligase complex. In addition to being ubiquitinated by the VHL-E3 ligase complex, this enzyme deubiquitinates hypoxia-inducible factor (HIF)-1 alpha and thereby causes increased expression of HIF-1alpha targeted genes which play a role in angiogenesis, glucose metabolism, cell proliferation and metastasis. The enzyme encoded by this gene also regulates G-protein coupled receptor signaling by mediating the deubiquitination of beta-2 adrenergic receptor (ADRB2). This enzyme is a ubiquitously expressed thiolester hydrolase. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jan 2013]
Synonyms
VDU2; hVDU2; LSFR3A

Cat.No. Product Name Price
SHH441352 shRNA set against Human USP20 (NM_006676.6) Inquiry
SHH441356 shRNA set against Mouse USP20 (NM_028846.5) Inquiry
SHH441360 shRNA set against Rat USP20 (NM_001107827.3) Inquiry
SHW017107 shRNA set against Danio rerio USP20 (NM_200987) Inquiry
Cat.No. Product Name Price
CDFH020939 Human USP20 cDNA Clone(NM_001008563.3) Inquiry
CDFH020941 Human USP20 cDNA Clone(NM_001110303.2) Inquiry
CDFH020944 Human USP20 cDNA Clone(NM_006676.6) Inquiry
MiUTR3H-15101 USP20 miRNA 3'UTR clone Inquiry
MiUTR3H-15102 USP20 miRNA 3'UTR clone Inquiry
MiUTR3H-15103 USP20 miRNA 3'UTR clone Inquiry
CDCB178582 Danio rerio USP20 ORF Clone (NM_200987) Inquiry
CDCB192813 Rabbit USP20 ORF clone (XM_008251714.1) Inquiry
CDCH098668 human USP20 ORF clone (NM_001008563.3) Inquiry
CDCR261952 Mouse Usp20 ORF Clone(NM_028846.5) Inquiry
CDCR293466 Human USP20 ORF Clone(NM_006676.6) Inquiry
CDCR347774 Human USP20 ORF Clone(NM_001110303.2) Inquiry
CDCR374502 Rat Usp20 ORF Clone(NM_001107827.3) Inquiry
CDCS406375 Human USP20 ORF Clone (BC039593) Inquiry
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