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unga


Official Full Name
uracil DNA glycosylase a
Organism
Danio rerio
Gene ID
393949
Background
Enables G/U mismatch-specific uracil-DNA glycosylase activity and histone H3K27 methyltransferase activity. Acts upstream of or within negative regulation of heterochromatin formation and positive regulation of DNA-templated transcription. Predicted to be active in mitochondrion and nucleus. Is expressed in blastomere; oocyte stage I; and oocyte stage II. Human ortholog(s) of this gene implicated in dysgammaglobulinemia and immunodeficiency with hyper IgM type 5. Orthologous to human UNG (uracil DNA glycosylase). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
ung; zgc:56102

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