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UCP2


Official Full Name
uncoupling protein 2
Organism
Homo sapiens
Gene ID
7351
Background
Mitochondrial uncoupling proteins (UCP) are members of the larger family of mitochondrial anion carrier proteins (MACP). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. Tissue specificity occurs for the different UCPs and the exact methods of how UCPs transfer H+/OH- are not known. UCPs contain the three homologous protein domains of MACPs. This gene is expressed in many tissues, with the greatest expression in skeletal muscle. It is thought to play a role in nonshivering thermogenesis, obesity and diabetes. Chromosomal order is 5'-UCP3-UCP2-3'. [provided by RefSeq, Jul 2008]
Synonyms
UCPH; BMIQ4; SLC25A8

Cat.No. Product Name Price
SHL104758 shRNA set against Human UCP2(NM_003355.2) Inquiry
SHL105040 shRNA set against Rat Ucp2(NM_019354.2) Inquiry
SHH439884 shRNA set against Human Ucp2 (NM_003355.2) Inquiry
SHH439888 shRNA set against Mouse Ucp2 (NM_011671.4) Inquiry
SHW014670 shRNA set against Danio rerio UCP2 (NM_131176) Inquiry
Cat.No. Product Name Price
CDFH020808 Human UCP2 cDNA Clone(NM_003355.2) Inquiry
CDFH020809 Human UCP2 cDNA Clone(NM_003355.2) Inquiry
CDFR011594 Rat Ucp2 cDNA Clone(NM_019354.2) Inquiry
MiUTR1H-10981 UCP2 miRNA 3'UTR clone Inquiry
MiUTR1R-08329 UCP2 miRNA 3'UTR clone Inquiry
SKO0054 UCP2 Validated sgRNA vector Inquiry
SKO0886 UCP2 Validated sgRNA vector Inquiry
CDCB176145 Danio rerio UCP2 ORF Clone (NM_131176) Inquiry
CDCB182391 Rabbit UCP2 ORF clone (XM_002708700.2) Inquiry
CDCR034806 Human UCP2 ORF clone (NM_003355.2) Inquiry
CDCR378641 Rat Ucp2 ORF Clone(NM_019354.2) Inquiry
CDCS411269 Human UCP2 ORF Clone (BC011737) Inquiry
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