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UBR1


Official Full Name
ubiquitin protein ligase E3 component n-recognin 1
Organism
Homo sapiens
Gene ID
197131
Background
The N-end rule pathway is one proteolytic pathway of the ubiquitin system. The recognition component of this pathway, encoded by this gene, binds to a destabilizing N-terminal residue of a substrate protein and participates in the formation of a substrate-linked multiubiquitin chain. This leads to the eventual degradation of the substrate protein. The protein described in this record has a RING-type zinc finger and a UBR-type zinc finger. Mutations in this gene have been associated with Johanson-Blizzard syndrome. [provided by RefSeq, Jul 2008]
Synonyms
JBS

Cat.No. Product Name Price
SHL103770 shRNA set against Human UBR1(NM_174916.2) Inquiry
SHH439520 shRNA set against Human UBR1 (NM_174916.2) Inquiry
SHH439527 shRNA set against Mouse UBR1 (NM_009461.2) Inquiry
SHH439528 shRNA set against Rat UBR1 (NM_001178072.1) Inquiry
SHL103788 shRNA set against Mouse Ubr1(NM_009461.2) Inquiry
Cat.No. Product Name Price
CDFG011070 Human UBR1 cDNA Clone(NM_174916.2) Inquiry
CDFL014618 Mouse Ubr1 cDNA Clone(NM_009461.2) Inquiry
MiUTR1H-10968 UBR1 miRNA 3'UTR clone Inquiry
MiUTR1M-12417 UBR1 miRNA 3'UTR clone Inquiry
CDCB194603 Rabbit UBR1 ORF clone (XM_008269117.1) Inquiry
CDCR247241 Mouse Ubr1 ORF Clone(NM_009461.2) Inquiry
CDCR322499 Human UBR1 ORF Clone(NM_174916.2) Inquiry
CDCS417487 Human UBR1 ORF Clone (BC113505) Inquiry
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