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UBE2R2

Official Full Name
ubiquitin conjugating enzyme E2 R2
Organism
Homo sapiens
GeneID
54926
Background
Protein kinase CK2 is a ubiquitous and pleiotropic Ser/Thr protein kinase involved in cell growth and transformation. This gene encodes a protein similar to the E2 ubiquitin conjugating enzyme UBC3/CDC34. Studies suggest that CK2-dependent phosphorylation of this ubiquitin-conjugating enzyme functions by regulating beta-TrCP substrate recognition and induces its interaction with beta-TrCP, enhancing beta-catenin degradation. [provided by RefSeq, Jul 2008]
Synonyms
UBC3B; CDC34B; E2-CDC34B;

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