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TSTA3

Official Full Name
tissue specific transplantation antigen P35B
Background
Tissue specific transplantation antigen P35B is a NADP(H)-binding protein. It catalyze the two-step epimerase and the reductase reactions in GDP-D-mannose metabolism, converting GDP-4-keto-6-D-deoxymannose to GDP-L-fucose. GDP-L-fucose is the substrate of several fucosyltransferases involved in the expression of many glycoconjugates, including blood group ABH antigens and developmental adhesion antigens. Mutations in this gene may cause leukocyte adhesion deficiency, type II.
Synonyms
TSTA3; tissue specific transplantation antigen P35B; GDP-L-fucose synthase; FX; GDP L fucose synthase; P35B; SDR4E1; short chain dehydrogenase/reductase family 4E; member 1; 3 5 epimerase/4 reductase; anti TSTA3; EC 1.1.1.271; GDP 4 keto 6 deoxy D mannose 35 epimerase 4 reductase; GDP 4 keto 6 deoxy D mannose epimerase reductase; Protein FX; Red cell NADP(H) binding protein; Tissue specific transplantation antigen 3; OTTHUMP00000228670; OTTHUMP00000228671; OTTHUMP00000228672; 3-5 epimerase/4-reductase; red cell NADP(H)-binding protein; GDP-4-keto-6-deoxy-D-mannose epimerase-reductase; GDP-4-keto-6-deoxy-D-manno; GDP-4-keto-6-deoxy-D-mannose-3,5-epimerase-4-reductase; short chain dehydrogenase/reductase family 4E, member 1; zgc:101805; si:dkey-235d18none;

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