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TRRAP

Official Full Name
transformation/transcription domain associated protein
Organism
Homo sapiens
GeneID
8295
Background
This gene encodes a large multidomain protein of the phosphoinositide 3-kinase-related kinases (PIKK) family. The encoded protein is a common component of many histone acetyltransferase (HAT) complexes and plays a role in transcription and DNA repair by recruiting HAT complexes to chromatin. Deregulation of this gene may play a role in several types of cancer including glioblastoma multiforme. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011]
Synonyms
Tra1; TR-AP; DEDDFA; DFNA75; PAF400; STAF40; PAF350/400;

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