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Trp53bp1

Official Full Name
transformation related protein 53 binding protein 1
Organism
Mus musculus
GeneID
27223
Background
Enables damaged DNA binding activity; methylated histone binding activity; and telomeric DNA binding activity. Involved in double-strand break repair via nonhomologous end joining; negative regulation of double-strand break repair via homologous recombination; and positive regulation of isotype switching. Acts upstream of or within DNA repair. Located in chromosome and nuclear body. Part of DNA repair complex. Is expressed in several structures, including ileum; liver; lung; nervous system; and sensory organ. Orthologous to human TP53BP1 (tumor protein p53 binding protein 1). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
Trp53bp1; 53BP1; m53BP1; p53BP1; Tp53bp1;

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