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TRIB2


Official Full Name
tribbles pseudokinase 2
Organism
Homo sapiens
Gene ID
28951
Background
This gene encodes one of three members of the Tribbles family. The Tribbles members share a Trb domain, which is homologous to protein serine-threonine kinases, but lacks the active site lysine and probably lacks a catalytic function. The Tribbles proteins interact and modulate the activity of signal transduction pathways in a number of physiological and pathological processes. This Tribbles member induces apoptosis of cells mainly of the hematopoietic origin. It has been identified as a protein up-regulated by inflammatory stimuli in myeloid (THP-1) cells, and also as an oncogene that inactivates the transcription factor C/EBPalpha (CCAAT/enhancer-binding protein alpha) and causes acute myelogenous leukemia. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2009]
Synonyms
C5FW; TRB2; GS3955

Cat.No. Product Name Price
AD16862Z Human TRIB2 adenoviral particles Inquiry
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SHH434328 shRNA set against Human TRIB2 (NM_021643.3) Inquiry
SHH434332 shRNA set against Mouse TRIB2 (NM_144551.5) Inquiry
SHH434336 shRNA set against Rat TRIB2 (NM_001108015.2) Inquiry
SHL092042 shRNA set against Mouse Trib2(NM_144551.5) Inquiry
SHW004914 shRNA set against Chicken TRIB2 (NM_204401) Inquiry
Cat.No. Product Name Price
CDFR007688 Rat Trib2 cDNA Clone(NM_001108015.2) Inquiry
MiUTR1M-12117 TRIB2 miRNA 3'UTR clone Inquiry
MiUTR3H-10621 TRIB2 miRNA 3'UTR clone Inquiry
CDCB166389 Chicken TRIB2 ORF Clone (NM_204401) Inquiry
CDCB183596 Rabbit TRIB2 ORF clone (XM_002710045.2) Inquiry
CDCL186623 Human TRIB2 ORF clone(NM_021643.3) Inquiry
CDCL186624 Mouse TRIB2 ORF clone(NM_144551.5) Inquiry
CDCR374665 Rat Trib2 ORF Clone(NM_001108015.2) Inquiry
CDCS415350 Human TRIB2 ORF Clone (BC002637) Inquiry
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