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TRAF3


Official Full Name
TNF receptor associated factor 3
Organism
Homo sapiens
Gene ID
7187
Background
The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from, members of the TNF receptor (TNFR) superfamily. This protein participates in the signal transduction of CD40, a TNFR family member important for the activation of the immune response. This protein is found to be a critical component of the lymphotoxin-beta receptor (LTbetaR) signaling complex, which induces NF-kappaB activation and cell death initiated by LTbeta ligation. Epstein-Barr virus encoded latent infection membrane protein-1 (LMP1) can interact with this and several other members of the TRAF family, which may be essential for the oncogenic effects of LMP1. The protein also plays a role in the regulation of antiviral response. Mutations in this are associated with Encephalopathy, acute, infection-induced, herpes-specific 5. [provided by RefSeq, Jul 2020]
Synonyms
CAP1; LAP1; CAP-1; CRAF1; IIAE5; CD40bp; RNF118

Cat.No. Product Name Price
SHH433708 shRNA set against Rat TRAF3 (NM_001108724.1) Inquiry
SHG056419 shRNA set against Mouse Traf3(NM_001048206.1) Inquiry
SHG056455 shRNA set against Mouse Traf3(NM_011632.2) Inquiry
SHH433700 shRNA set against Human TRAF3 (NM_003300.3) Inquiry
SHH433704 shRNA set against Mouse TRAF3 (NM_011632.2) Inquiry
SHW006840 shRNA set against Danio rerio TRAF3 (NM_001003513) Inquiry
Cat.No. Product Name Price
CDFG018658 Mouse Traf3 cDNA Clone(NM_001048206.1) Inquiry
CDFR008312 Rat Traf3 cDNA Clone(NM_001108724.1) Inquiry
MiUTR1M-12077 TRAF3 miRNA 3'UTR clone Inquiry
MiUTR1M-12078 TRAF3 miRNA 3'UTR clone Inquiry
MiUTR3H-04485 TRAF3 miRNA 3'UTR clone Inquiry
MiUTR3H-04486 TRAF3 miRNA 3'UTR clone Inquiry
MiUTR3H-04487 TRAF3 miRNA 3'UTR clone Inquiry
CDCB168315 Danio rerio TRAF3 ORF Clone (NM_001003513) Inquiry
CDCB182449 Rabbit TRAF3 ORF clone (XM_002721716.2) Inquiry
CDCG003714 Human TRAF3 ORF clone(NM_145725.2) Inquiry
CDCH094482 human TRAF3 ORF clone (NM_001199427.1) Inquiry
CDCR027260 Mouse Traf3 ORF clone (NM_001048206.1) Inquiry
CDCR027262 Mouse Traf3 ORF clone (NM_011632.2) Inquiry
CDCR375355 Rat Traf3 ORF Clone(NM_001108724.1) Inquiry
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