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TPO


Official Full Name
thyroid peroxidase
Organism
Homo sapiens
Gene ID
7173
Background
This gene encodes a membrane-bound glycoprotein. The encoded protein acts as an enzyme and plays a central role in thyroid gland function. The protein functions in the iodination of tyrosine residues in thyroglobulin and phenoxy-ester formation between pairs of iodinated tyrosines to generate the thyroid hormones, thyroxine and triiodothyronine. Mutations in this gene are associated with several disorders of thyroid hormonogenesis, including congenital hypothyroidism, congenital goiter, and thyroid hormone organification defect IIA. Multiple transcript variants encoding distinct isoforms have been identified for this gene, but the full-length nature of some variants has not been determined. [provided by RefSeq, May 2011]
Synonyms
MSA; TPX; TDH2A

Cat.No. Product Name Price
SHH433372 shRNA set against Human TPO (NM_000547.5) Inquiry
SHH433376 shRNA set against Mouse TPO (NM_009417.2) Inquiry
SHH433380 shRNA set against Rat TPO (NM_019353.2) Inquiry
SHL089994 shRNA set against Mouse Tpo(NM_009417.2) Inquiry
Cat.No. Product Name Price
CDFL014185 Mouse Tpo cDNA Clone(NM_009417.2) Inquiry
MiUTR1M-12069 TPO miRNA 3'UTR clone Inquiry
MiUTR3H-08699 TPO miRNA 3'UTR clone Inquiry
MiUTR3H-08700 TPO miRNA 3'UTR clone Inquiry
MiUTR3H-08701 TPO miRNA 3'UTR clone Inquiry
CDCB182687 Rabbit TPO ORF clone (XM_008252580.1) Inquiry
CDCL186601 Human TPO ORF clone(NM_000547.5) Inquiry
CDCR247194 Mouse Tpo ORF Clone(NM_009417.2) Inquiry
CDCR322714 Human TPO ORF Clone(NM_175719.3) Inquiry
CDCR322717 Human TPO ORF Clone(NM_175721.3) Inquiry
CDCR322719 Human TPO ORF Clone(NM_175722.3) Inquiry
CDCR378640 Rat Tpo ORF Clone(NM_019353.2) Inquiry
CDCS405735 Human TPO ORF Clone (BC063107) Inquiry
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