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TNNI2


Official Full Name
troponin I2, fast skeletal type
Organism
Homo sapiens
Gene ID
7136
Background
This gene encodes a fast-twitch skeletal muscle protein, a member of the troponin I gene family, and a component of the troponin complex including troponin T, troponin C and troponin I subunits. The troponin complex, along with tropomyosin, is responsible for the calcium-dependent regulation of striated muscle contraction. Mouse studies show that this component is also present in vascular smooth muscle and may play a role in regulation of smooth muscle function. In addition to muscle tissues, this protein is found in corneal epithelium, cartilage where it is an inhibitor of angiogenesis to inhibit tumor growth and metastasis, and mammary gland where it functions as a co-activator of estrogen receptor-related receptor alpha. This protein also suppresses tumor growth in human ovarian carcinoma. Mutations in this gene cause myopathy and distal arthrogryposis type 2B. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2009]
Synonyms
DA2B; FSSV; DA2B1; fsTnI; AMCD2B

Cat.No. Product Name Price
SHH432380 shRNA set against Human TNNI2 (NM_003282.3) Inquiry
SHH432384 shRNA set against Mouse TNNI2 (NM_009405.2) Inquiry
SHH432388 shRNA set against Rat TNNI2 (NM_017185.1) Inquiry
SHL086462 shRNA set against Rat Tnni2(NM_017185.1) Inquiry
SHL086480 shRNA set against Mouse Tnni2(NM_009405.2) Inquiry
SHW005911 shRNA set against Chicken TNNI2 (NM_205417) Inquiry
Cat.No. Product Name Price
CDCH093726 Mouse Tnni2 ORF clone (NM_009405.2) Inquiry
CDFH020056 Human TNNI2 cDNA Clone(NM_001145829.1) Inquiry
CDFH020057 Human TNNI2 cDNA Clone(NM_001145841.1) Inquiry
CDFR011237 Rat Tnni2 cDNA Clone(NM_017185.1) Inquiry
MiUTR1M-12022 TNNI2 miRNA 3'UTR clone Inquiry
MiUTR1R-08136 TNNI2 miRNA 3'UTR clone Inquiry
MiUTR3H-02298 TNNI2 miRNA 3'UTR clone Inquiry
MiUTR3H-02299 TNNI2 miRNA 3'UTR clone Inquiry
MiUTR3H-02300 TNNI2 miRNA 3'UTR clone Inquiry
CDCB167386 Chicken TNNI2 ORF Clone (NM_205417) Inquiry
CDCB180201 Rabbit TNNI2 ORF clone (NM_001082783.1) Inquiry
CDCR027140 Human TNNI2 ORF clone (NM_001145841.1) Inquiry
CDCR353095 Human TNNI2 ORF Clone(NM_001145829.1) Inquiry
CDCR378251 Rat Tnni2 ORF Clone(NM_017185.1) Inquiry
CDCS408556 Human TNNI2 ORF Clone (BC032148) Inquiry
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