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TMBIM6

Official Full Name
transmembrane BAX inhibitor motif containing 6
Organism
Homo sapiens
GeneID
7009
Background
Enables endoribonuclease inhibitor activity and ubiquitin protein ligase binding activity. Involved in several processes, including negative regulation of intrinsic apoptotic signaling pathway; negative regulation of macromolecule metabolic process; and response to L-glutamate. Acts upstream of or within negative regulation of calcium ion transport into cytosol. Located in endoplasmic reticulum membrane. Biomarker of cervical squamous cell carcinoma and prostate carcinoma. [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
BI-1; TEGT; BAXI1;

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