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TERF1

Official Full Name
telomeric repeat binding factor 1
Organism
Homo sapiens
GeneID
7013
Background
This gene encodes a telomere specific protein which is a component of the telomere nucleoprotein complex. This protein is present at telomeres throughout the cell cycle and functions as an inhibitor of telomerase, acting in cis to limit the elongation of individual chromosome ends. The protein structure contains a C-terminal Myb motif, a dimerization domain near its N-terminus and an acidic N-terminus. Multiple transcripts of this gene are alternatively spliced products. [provided by RefSeq, Aug 2022]
Synonyms
TRF; PIN2; TRF1; TRBF1; t-TRF1; hTRF1-AS;

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