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Tcfe3


Official Full Name
transcription factor E3
Organism
Mus musculus
Gene ID
209446
Background
Enables DNA-binding transcription factor activity; E-box binding activity; and protein heterodimerization activity. Involved in several processes, including negative regulation of cold-induced thermogenesis; positive regulation of brown fat cell differentiation; and positive regulation of transcription by RNA polymerase II. Acts upstream of or within regulation of osteoclast differentiation. Located in cytosol and nucleus. Is expressed in several structures, including adipose tissue; branchial arch; early conceptus; genitourinary system; and gut. Human ortholog(s) of this gene implicated in renal cell carcinoma. Orthologous to human TFE3 (transcription factor binding to IGHM enhancer 3). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
Tfe3; Tcfe3; Tfe-3; mTFE3; bHLHe33; F830016E06Rik

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