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TAX1BP3


Official Full Name
Tax1 binding protein 3
Organism
Homo sapiens
Gene ID
30851
Background
This gene encodes a small, highly conserved protein with a single PDZ domain. PDZ (PSD-95/Discs large/ZO-1 homologous) domains promote protein-protein interactions that affect cell signaling, adhesion, protein scaffolding, and receptor and ion transporter functions. The encoded protein interacts with a large number of target proteins that play roles in signaling pathways; for example, it interacts with Rho A and glutaminase L and also acts as a negative regulator of the Wnt/beta-catenin signaling pathway. This protein was first identified as binding to the T-cell leukaemia virus (HTLV1) Tax oncoprotein. Overexpression of this gene has been implicated in altered cancer cell adhesion, migration and metastasis. The encoded protein also modulates the localization and density of inwardly rectifying potassium channel 2.3 (Kir2.3). To date, this protein has been shown to play a role in cell proliferation, development, stress response, and polarization. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Apr 2017]
Synonyms
TIP1; TIP-1

Cat.No. Product Name Price
SHH423672 shRNA set against Human TAX1BP3 (NM_014604.3) Inquiry
SHH423676 shRNA set against Mouse TAX1BP3 (NM_029564.2) Inquiry
SHH423680 shRNA set against Rat TAX1BP3 (NM_001025419.1) Inquiry
SHL058150 shRNA set against Rat Tax1bp3(NM_001025419.1) Inquiry
SHL058220 shRNA set against Mouse Tax1bp3(NM_029564.2) Inquiry
SHW018524 shRNA set against Danio rerio TAX1BP3 (NM_213470) Inquiry
Cat.No. Product Name Price
CDFR003972 Rat Tax1bp3 cDNA Clone(NM_001025419.1) Inquiry
MiUTR1M-11560 TAX1BP3 miRNA 3'UTR clone Inquiry
MiUTR1R-07914 TAX1BP3 miRNA 3'UTR clone Inquiry
MiUTR3H-15659 TAX1BP3 miRNA 3'UTR clone Inquiry
CDCB179999 Danio rerio TAX1BP3 ORF Clone (NM_213470) Inquiry
CDCB186762 Rabbit TAX1BP3 ORF clone (XM_002718865.2) Inquiry
CDCR262588 Mouse Tax1bp3 ORF Clone(NM_029564.2) Inquiry
CDCR370947 Rat Tax1bp3 ORF Clone(NM_001025419.1) Inquiry
CDCS409629 Human TAX1BP3 ORF Clone (BC023980) Inquiry
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