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TAF1C

Official Full Name
TATA-box binding protein associated factor, RNA polymerase I subunit C
Organism
Homo sapiens
GeneID
9013
Background
Initiation of transcription by RNA polymerase I requires the formation of a complex composed of the TATA-binding protein (TBP) and three TBP-associated factors (TAFs) specific for RNA polymerase I. This complex, known as SL1, binds to the core promoter of ribosomal RNA genes to position the polymerase properly and acts as a channel for regulatory signals. This gene encodes the largest SL1-specific TAF. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2011]
Synonyms
SL1; TAFI95; TAFI110; MGC:39976;

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