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TRIT1

Official Full Name
tRNA isopentenyltransferase 1
Organism
Homo sapiens
GeneID
54802
Background
This gene encodes a protein that that is targeted to the mitochondrion and modifies transfer RNAs (tRNAs) by adding a dimethylallyl group onto the adenine at position 37. This modification is important for maintaining the correct reading frame during protein translation. This gene is considered a tumor suppressor and its expression can decrease cell growth. Alternative splicing results in multiple transcripts variants, most of which are likely non-functional. [provided by RefSeq, Aug 2015]
Synonyms
IPT; GRO1; IPPT; MOD5; hGRO1; IPTase; COXPD35;

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